About the MUGgLE study

The MUGgLE study is a research study on growth of muscles and tendons during childhood development. We are studying muscles of typically developing children and of children with cerebral palsy using MRI scans of the lower legs.

The MUGgLE study is a collaboration between researchers at Cerebral Palsy Alliance Research Institute, University of New South Wales and Neuroscience Research Australia (NeuRA). The study will be conducted at NeuRA’s Imaging Facility in Randwick (Sydney), Australia.

The aims of the MUGgLE study are to:

  1. describe growth-related changes in the three-dimensional architecture of leg muscles of typically developing children,
  2. compare growth-related changes in muscle architecture in children with cerebral palsy and typically developing children, and
  3. identify causes of impaired muscle growth in children with cerebral palsy.

This study has been funded by the National Health and Medical Research Council of Australia (APP1156394) and is approved by the Sydney Children’s Hospital Network Human Research Ethics Committee (2019/ETH11705).